Published: 12 June 2024
Author(s): Fulvio Morello, Paolo Bima, Matteo Castelli, Elisa Capretti, Alexandre de Matos Soeiro, Alessandro Cipriano, Giorgio Costantino, Simone Vanni, Bernd A. Leidel, Beat A. Kaufmann, Adi Osman, Marcello Candelli, Nicolò Capsoni, Wilhelm Behringer, Marialessia Capuano, Giovanni Ascione, Tatiana de Carvalho Andreucci Torres Leal, Lorenzo Ghiadoni, Emanuele Pivetta, Stefano Grifoni, Enrico Lupia, Peiman Nazerian, PROFUNDUS Study Investigators
Section: Original Article

Acute aortic syndromes (AASs), including aortic dissection (AD), intramural aortic haematoma (IMH) and penetrating aortic ulcer (PAU), affect 5–7/100,000 individuals/year [1]. They are time-dependent emergencies burdened by up to 1–2 % mortality/hour, if left untreated. AASs cause unspecific symptoms such as chest/abdominal/back pain, syncope, neurological deficits and limb ischemia. Large numbers of patients are evaluated in Emergency Departments (EDs) for these common symptoms, but only few of them have an AAS, e.g.

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