In hypertensive patients with reflex syncope, detection of transient hypotension as possible trigger mechanism of syncope may prompt deprescribing of hypotensive medications to counteract the risk of excessive BP falls [1]. A recent study from our group investigated the use of 24-hour ambulatory BP monitoring (ABPM) in this clinical context and demonstrated that reflex syncope patients more frequently show daytime, and 24-hour systolic (S) BP drops on ABPM compared with non-syncopal individuals [2].