Published: 31 October 2017
Author(s): Alessandra Vecchié, Franco Dallegri, Federico Carbone, Aldo Bonaventura, Luca Liberale, Piero Portincasa, Gema Frühbeck, Fabrizio Montecucco
Issue: October 2017
Section: Narrative Review

The pro-inflammatory state of the visceral adipose tissue (VAT) is supposed to accelerate cardiovascular (CV) and metabolic diseases in obese subjects. Some studies have recently reported an improved CV prognosis in certain obese and overweight patients as compared with leaner ones. This phenomenon, known as the “obesity paradox” (OP), has been described in many chronic diseases. This narrative review is based on the material searched for and obtained via PubMed and Web of Science up to May 2017.


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