Usually in stable and asymptomatic patient with reduced ejection fraction the judgment to suspend or not diuretic therapy purely depend on clinical and intuitive evaluation and not on objective parameters. In clinical practice diuretic treatment in stable heart failure with reduced ejection fraction (HFrEF) patients is being used without clear evidence of major benefit on cardiovascular morbidity and mortality, due to the absence of adequately sized trials addressing these questions. In our study we support the concept that diuretics withdrawal should be performed in this HFrEF patients especially when adequate fluid balance is achieved [1].
