Previous studies have shown an incidence of saddle pulmonary embolism (SPE) ranging between 6% to 9.1% in non-high-risk patients [1,2]. SPE is generally defined as a thromboembolus straddling the bifurcation of the main pulmonary artery trunk. Conversely, central PE is diagnosed when thrombi are visualized at computed tomography angiography (CTA) in the main trunk and/or in right or left main pulmonary arteries [3]. Its real epidemiology has not yet been assessed since, very frequently, the diagnosis is established at autopsy.