Cardiovascular disease (CVD) remains the leading cause of death in developed countries[1]. For the prevention of CVD, accurate identification of individuals at increased CVD risk is essential, in order to aggressively target their risk factors. Several risk scores have been developed to achieve this goal. The current European guidelines recommend Systematic Coronary Risk Evaluation (SCORE) for CVD risk estimation in European countries[2,3]. This score is based on 12 European cohort studies representing 2.7 million person years of follow-up[4].
