Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune condition characterized by a wide range of cytokines and antibodies production. The interleukin 10 (IL-10) is one of the most studied cytokines, with pleiomorphic functions, also involved in lymphocytes cell growth and differentiation. Most studies identified higher IL-10 levels in lupus patients when compared to control subjects and also significant correlations of serum IL-10 with lupus disease activity and anti-DNA titers (revised by Peng et al) [1].
