Published: 24 November 2022
Author(s): François Rodrigues, Jérémie Sellam, Pierre Quartier, Stéphanie Ducharme-Bénard, Sophie Georgin-Lavialle
Issue: April 2023
Section: Letter to the Editor

Familial Mediterranean fever (FMF) is a monogenic autoinflammatory disorder that is linked to homozygous mutations of the MEFV gene [1]. The field of FMF is expanding as many patients with FMF phenotype are heterozygous with monoallelic variants. Arthritis is a frequent manifestation of FMF, involving 50 to 75% of patients [2]. The hip is the third most commonly affected joint after the knee and ankle [2]. Aseptic necrosis of the femoral head [3] caused by disruption of local blood supply has also been reported in FMF patients.

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