SARS-CoV-2 descended on humanity in 2020 as an acute virus causing millions of excess deaths and suffering [1]. Early research into antibody use, antivirals and the development of vaccines lead to fewer deaths, less hospitalization and severe disease [2,3]. Over time the immunity of the population has improved, variants appear to be less virulent with most people getting back to “normal”. While physicians fought the early battle against severe acute infection, a subgroup of people appeared. These were people who recovered from acute coronavirus disease 2019 (COVID-19) infection but then developed a vague but often debilitating constellation of symptoms [4].
