A forty-five year-old man, with a tobacco and alcohol history, affected with Crohn's disease, was admitted for haemoptysis and abdominal pain. The clinical examination showed extensive cutaneous purpuric lesions (Fig. 1A) and a purple-coloured palate with gingival inflammation (Fig. 1B). Biological analyses revealed an elevation of the C-reactive protein, at 15mg/l, an icteric cholestasis with cytolysis and severe malnutrition demonstrated by a hypoalbuminemia of 21g/l. The chest CT-scan showed slight ground glass opacity in the apex, and the abdominal CT-scan showed a non-specific and moderate colitis.