In patients with acute pulmonary embolism (PE), both the prognostic stratification and reperfusion treatment are mainly based on the hemodynamic profile at admission, which is assessed using the systolic blood pressure (SBP) value [1]. However, SBP has some intrinsic limitations, being not able to evaluate two-thirds of the cardiac cycle, represented by the diastolic phase. Intermediate-high risk PE patients have generated a growing debate over the last years regarding the need of a more aggressive treatment during the acute phase of the disease [2].
