April 2020
9 ArticlesCommentary
Alcohol intake and atrial fibrillation: A new topic in gender medicine
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia in clinical practice and a major risk factor for stroke, heart failure, hospitalization and mortality [1–3]. It affects... more
Prolyl-hydroxylase domain inhibitors in chronic kidney disease, a promising alternative for erythropoiesis-stimulating agent
Anemia is one of the most common complications during chronic kidney disease (CKD) and results from a progressive lack of erythropoietin (EPO). EPO plays a major role in erythropoiesis by inducing... more
Risk stratification vs routine intensive care stay in non ST segment elevation myocardial infarction (NSTEMI)
Non-ST-segment-elevation acute coronary syndromes (NSTE ACS) encompass a wide spectrum of clinical conditions characterised by acute ischemic symptoms, electrocardiographic signs of myocardial... more
Letter to the Editor
SARS-CoV-2 detection in the pericardial fluid of a patient with cardiac tamponade
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a novel coronavirus first identified in Wuhan, China, at the end of 2019. Since then it has caused more than 1,700,000 confirmed cases... more
Factors associated with mortality in patients with COVID-19. A quantitative evidence synthesis of clinical and laboratory data
The COVID-19 pandemic caused by the severe acute respiratory coronavirus 2 (SARS-CoV-2) has become a serious challenge for health systems worldwide. Despite the favorable clinical course for most... more
Is low sodium intake a risk factor for severe and fatal COVID-19 infection?
As of March 16th, the number of deaths due to the coronavirus 2019 (COVID-19) outside China has surpassed those in China. Intriguingly, recent calculations that adjust for an incubation period of up... more
Review Article
Antisense lipoprotein[a] therapy: State-of-the-art and future perspectives
Lipoprotein[a] (Lp[a]) is an enigmatic low density lipoprotein (LDL)-like particle, in which apolipoprotein B100 (apoB100), the main protein moiety of LDL, is covalently linked through a single... more
The pivotal link between ACE2 deficiency and SARS-CoV-2 infection
Angiotensin converting enzyme-2 (ACE2) receptors mediate the entry into the cell of three strains of coronavirus: SARS-CoV, NL63 and SARS-CoV-2. ACE2 receptors are ubiquitous and widely expressed in... more
The challenge of implementing Less is More medicine: A European perspective
Healthcare systems in developed countries are facing new challenges that include defining the values, objectives and tasks of sustainable medicine. Near universal access to quality health care is one... more