The term “amyloidosis” encompasses a large group of diseases characterized by extracellular deposition of fibrillar proteins impairing organ function. Classification of amyloidosis relies on the nature of the protein and the deposition site. Systemic amyloidosis includes mainly immunoglobulin light chains (AL) amyloidosis, transthyretin (TTR) amyloidosis, either wild-type or hereditary, and “reactive” amyloid A (AA) amyloidosis [1, 2].