Published: 17 August 2018
Author(s): Wilma Barcellini, Giulio Pezzetti, Bruno Fattizzo, Francesca Cavallaro, Francesco De Cobelli
Issue: August 2018
Section: Letter to the Editor

Thrombosis is the leading cause of morbidity and mortality in paroxysmal nocturnal hemoglobinuria (PNH), accounting for 40–67% of deaths and is frequently observed in atypical sites, such as abdominal and intracranial veins [1]. Moreover, microvascular thrombosis are thought to be responsible for typical PNH presenting symptoms as dysphagia, abdominal pain, headache, and erectile dysfunction. There is now increasing interest in the identification of subclinical ischemic lesions by mean of highly sensitive radiologic techniques.


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