The prevalence and incidence of type 2 diabetes mellitus (T2DM) are increasing worldwide, and an estimated 50% of patients remain unaware of their disease [1]. T2DM is a highly prevalent chronic disease associated with major long-term complications, whose prevalence has risen substantially in many countries [2], although some studies indicate stabilization or reduction in certain populations [3]. Nowadays, diabetes is a priority health threat; the leading cause of end stage renal disease, it is also the most frequent cause of new-onset blindness among adults aged 20–74 years in developed countries, and is associated with increased risk of cardiovascular disease [4].
