Patients with clinically suspected pulmonary embolism (PE) should be managed according to standardized flowcharts. These flowcharts include validated algorithms to determine pretest probability, d-dimer testing (in patients with non–high clinical probability), and subsequent computed tomography pulmonary angiography (CTPA) if indicated [1]. A low clinical probability combined with a negative d-dimer value safely excludes PE without the need for radiologic imaging [2].
