A 78-year-old woman presented to the author's hospital with epigastralgia. Vital signs were normal and the patient's abdomen was soft. The patient had taken dabigatran 110mg twice daily due to atrial fibrillation for 2years. Esophagogastroduodenoscopy (EGD) revealed longitudinal sloughing mucosal casts in the mid and lower esophagus (Fig. 1, Panel A and B).