Legalization of medical or recreational use of marijuana presupposes that all drug-formulations have been tested and proven safe. However, this has not been the case with this substance, and to be fair, with other substances (e.g. tobacco) or drugs as well, which are plagued by various adverse effects. At least, when the medicinal use of cannabis is considered, its adverse events should be weighed against the adverse events of the currently available medicines. Unfortunately, regarding cannabis, accumulated evidence to-date converges to a rather dismal outlook [1].
