A 47-year-old woman presented to the emergency department of the author's hospital with severe disorder of consciousness. She had been epileptic since early childhood and had many epileptic family members. Thus, she had been receiving anticonvulsants such as carbamazepine (CBZ) and diazepam. Her Glasgow coma scale on admission was 5 (E1V1M3). Brain computed tomography revealed no abnormalities, and electroencephalography revealed no seizure activity. An electrocardiogram showed normal sinus rhythm.