Published: 7 August 2020
Author(s): Maria Teresa Chiarelli, Stefania Antoniazzi, Laura Cortesi, Luca Pasina, Alessio Novella, Francesca Venturini, Alessandro Nobili, Pier Mannuccio Mannucci, the ad hoc Deprescribing Study Group
Issue: January 2021
Section: Original article

Older patients, the largest fraction of those acutely admitted to hospital medical wards, are often affected by multiple chronic diseases, that are in turn associated with the intake of multiple drugs [1]. Polypharmacy stems from the cumulative prescription of the drugs recommended by the guidelines for each single disease that makes up multimorbidity [2,3]. Another cause is the frequent fragmentation of prescriptions made by the different specialists often attending multimorbid older patients, with poor coordination and integration between them and generalist physicians such as internists, geriatricians and general practitioners in the implementation of an holistic strategy of medication review [4].


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