Atrial fibrillation (AF) is the most common cardiac arrythmia, with an estimate of 37.6 million cases (0.51% of the world population) in 2017. Its prevalence has increased by 33% in the last 20 years and future projections suggest that the burden could increase by more than 60% by 2050. AF is associated with an increased risk of stroke, cardiovascular disease, renal disease, and mortality. Thus, primary prevention of AF would be an important measure to reduce healthcare burden. In recent times, researchers have investigated whether dietary supplements have a role in the prevention of AF.