Acute ischemic stroke is a major health burden worldwide due to high rates of ensuing hospitalizations, complications, disability, dependency, and death [1]. Venous thromboembolism (VTE), which comprises deep vein thrombosis (DVT) and pulmonary embolism (PE), represents a frequent complication in patients with stroke and is associated with significant morbidity and mortality [2]. In these patients, hospitalization, immobilization, and other medical sequelae deriving from the neurological deficits may increase VTE risk up to threefold compared to patients without stroke [3,4].