Sex differences affect patient outcomes in many diseases, such as Coronavirus Disease 2019 (COVID-19), acute myocardial infarction, acute ischemic stroke and infectious diseases, while outcome differences in out of hospital cardiac arrest are still controversial [1–7]. Male sex was found to be an independent predictor of mortality in the Emergency Department (ED) [8–11], but it is unclear whether this higher risk for men is caused by male sex itself, by higher disease severity at ED presentation, or by sex related differences in the recognition and treatment of patients at risk in the ED.
