The monkeypox outbreak during the coronavirus disease 2019 (COVID-19) pandemic has given rise to the concern of multiple viral pandemics. Though COVID-19 has been around for three years by now, mass immunization and precautionary measures have played a pivotal role in tackling an emerging global panic. However, recently an unprecedented outbreak of monkeypox has occurred in areas that are not endemic to the disease. This has given rise to the concern that the world is most likely to enter a stage of a new viral pandemic, which is not only alarming but has also urged the healthcare professionals to speed up the research regarding its prevention and treatment much more effectively.