January 2023

35 Articles

Book review

WITHDRAWN: Reprint of: Differential diagnosis by laboratory medicine: a quick reference for physicians

16 August 2011
Author(s): J.W.F. Elte

This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause.

Case Report

WITHDRAWN: Reprint of: Bone metastasis of a follicular thyroid carcinoma originated in a toxic multinodular goiter

16 August 2011
Author(s): T.S. Schmitt, J.W.F. Elte, A.P. Rietveld, H.C.T. van Zaanen, M. Castro Cabezas

This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause.

Clinical Insights

Natural history of ‘silent’ atrial fibrillation from subclinical to asymptomatic: State of the art and need for research

17 November 2022
Author(s): Marco Proietti

In the last 30 years clinical research in the atrial fibrillation (AF) field has seen a great advance both in terms of productivity and heterogeneity of areas that developed significant new knowledge... more

Editorial

WITHDRAWN: Reprint of: Diagnosis of Cushing's syndrome

16 August 2011
Author(s): J.W.F. Elte

This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause.

Internal Medicine Flashcard

Blurred vision: Hitting the bull's eye

13 October 2022
Author(s): Ritu Kapil, Anish Kapil

An 18-year-old female presented with progressive blurred vision in both eyes. On evaluation, her uncorrected visual acuity was 20/400 in both eyes. Slit lamp examination revealed bilateral supero-... more

Acute necrosis of the corpus callosum

12 October 2022
Author(s): Nicolas Lambert, Martin Moïse

A 58-year-old man with a history of alcohol use disorder was admitted for apathy, confusion and aphasia of abrupt onset. In addition, clinical examination revealed a tetrapyramidal syndrome. Blood... more

Internal Medicine in Europe

WITHDRAWN: Reprint of: The history of the (Young) AEMI(E) and the EFIM

16 August 2011
Author(s): Ugo E.F. Carcassi, Jan Willem F. Elte, Christopher Davidson

This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause.

Letter to the Editor

How the theory of centralized aerobic-anaerobic energy balance compensation explains sudden cardiac death in young athletes

2 November 2022
Author(s): Alexandre A Vetcher, Kirill V. Zhukov, Bagrat A. Gasparyan, Alexander Y. Shishonin

This letter should be considered as a follow up comment to the recent publication in the European Journal of Internal Medicine on sudden cardiac death (SCD) in young athletes [1]. The issue of SCD in... more

Informed consent process in the I-SPY COVID trial is questionable

22 October 2022
Author(s): Rafael Dal-Ré, Arthur L Caplan, Teck Chuan Voo

We read with interest the letter by Files et al. [1] commenting on our recently published article in which we discussed the inappropriateness of randomizing trial participants before obtaining their... more

Monkeypox infection: Should we expect changes in its epidemiological and clinical features?

18 October 2022
Author(s): Maria Gabriella Donà, Eugenia Giuliani, Mauro Zaccarelli, Alessandra Latini

We read with interest the excellent review on the outbreak of monkeypox (MPX) by Patauner et al. [1]. The epidemiological scenario was exhaustively described but referred to a pre-vaccination era. In... more

Informed consent process in the ISPY COVID trial is ethically acceptable

30 September 2022
Author(s): D. Clark Files, Laura Esserman, Kathleen D. Liu, Carolyn S. Calfee

The ISPY COVID Investigators would like to respond to Dal-Re et al. in their recent editorial in on the ethics of the consent process in the ISPY COVID Trial [1]. Unfortunately, the authors of the... more

Monkeypox infections in vulnerable groups

24 September 2022
Author(s): Brendan Bryan Jen-Wei Tan, Ling-Ling Chan, Eng-King Tan

Dear editor,

Can a smallpox drug treat monkeypox? Compassionate use of tecovirimat for monkeypox infection

21 September 2022
Author(s): Maurish Fatima, Aleena Ahmed, Muhammad Wahaj Murad, Zeeshan Afzal

The monkeypox outbreak during the coronavirus disease 2019 (COVID-19) pandemic has given rise to the concern of multiple viral pandemics. Though COVID-19 has been around for three years by now, mass... more

Harm of early dexamethasone for COVID-19 and bias in randomized trials

18 September 2022
Author(s): Isaac Núñez, Yanink Caro-Vega, Adrian Soto-Mota

Numerous unproven therapies for coronavirus disease 2019 (COVID-19) were adopted early on based on inadequate evidence [1]. The Randomized Evaluation of COVID-19 Therapy (RECOVERY) is a large simple... more

Multi-country monkeypox outbreak: A quantitative evidence synthesis on clinical characteristics, potential transmission routes, and risk factors

17 September 2022
Author(s): Paulo Ricardo Martins-Filho, Diego Moura Tanajura, Gonzalo Vecina-Neto

The world is facing an outbreak of monkeypox. Since early May 2022, more than 60,000 cases of monkeypox have been reported from countries where the disease is not endemic. Monkeypox is a zoonotic... more

Variability in blood testing policy in internal medicine and clinical outcomes

15 September 2022
Author(s): Jacob David Miller, Daniel Ostrovsky, Michael Murninkas, Victor Novack

Dear Editor,

Long-standing thrombocytosis often precedes thromboembolic complications heralding the diagnosis of essential thrombocythemia

15 September 2022
Author(s): Gregoire Stalder, William Reis Da Silva, Amandine Segot, Sabine Blum, Francesco Grandoni, Lorenzo Alberio

Myeloproliferative neoplasms (MPN) are clonal diseases of hematopoietic stem cells characterized by the hyperplasia of one or more myeloid cell lines that retain their capacity for terminal... more

Characteristics of JAK2 unmutated erythrocytosis: Distinctive traits between polycythemia vera and non-polycythemia vera patients

9 September 2022
Author(s): Vincent Ernest, Norman Abbou, Antoine Tichadou, Robin Arcani, Geoffroy Venton

Polycythemia is a frequent reason for consultation, and is related to various etiologies. Erythropoietin (EPO) plays a major role in the physiological stimulation of red blood cell (RBC) progenitors... more

WITHDRAWN: Reprint of: Detrimental action of thiazolidinediones on bone (rebuttal)

16 August 2011
Author(s): J.W.F. Elte, J.F. Blicklé

This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause.

Original Article

Time-trends in disease characteristics and comorbidities in patients with chronic hepatitis B in the period 1980–2020

14 November 2022
Author(s): D.P.C. van der Spek, W.K. Katwaroe, L.A. van Kleef, S. Brakenhoff, R.A. de Man, R.J. de Knegt, A.J. van der Meer, M.J. Sonneveld

the American Association for the Study of Liver Diseases

Airflow grades, outcome measures and response to pulmonary rehabilitation in individuals after an exacerbation of severe chronic obstructive pulmonary disease

14 November 2022
Author(s): Michele Vitacca, Mara Paneroni, Beatrice Salvi, Antonio Spanevello, Piero Ceriana, Claudio Bruschi, Bruno Balbi, Maria Aliani, Nicolino Ambrosino

Individuals with Chronic obstructive pulmonary disease (COPD) are staged according to symptoms and exacerbation (ECOPD) history, (Global Initiative for Chronic Obstructive Lung Disease (GOLD) groups... more

Impact of ABC (Atrial Fibrillation Better Care) pathway adherence in high-risk subgroups with atrial fibrillation: A report from the ESC-EHRA EORP-AF long-term general registry

10 November 2022
Author(s): Wern Yew Ding, Marco Proietti, Giulio Francesco Romiti, Marco Vitolo, Ameenathul Mazaya Fawzy, Giuseppe Boriani, Francisco Marin, Carina Blomström-Lundqvist, Tatjana S. Potpara, Laurent Fauchier, Gregory Y. H Lip, ESC-EHRA EORP-AF Long-Term General Registry Investigators

Atrial fibrillation (AF) is a significant public health issue with a global prevalence of 33.5 million patients affected by the condition and approximately 5 million new cases identified each year [1... more

Effects and differences of sleep duration on the risk of new-onset chronic disease conditions in middle-aged and elderly populations

8 November 2022
Author(s): Yaoling Wang, Gege Jiang, Niuniu Hou, Minfang Chen, Kang Yang, Kai Wen, Yujie Lan, Wei Li

It is expected that by 2050 the population over 65 in China will reach 400 million [1]. A recent epidemiological study in China has demonstrated that 75.8% of residents over 60 years old suffer from... more

Post-operative recurrence of liver cancer according to antiviral therapy for detectable hepatitis B viremia: A nationwide study

5 November 2022
Author(s): Byungyoon Yun, Sang Hoon Ahn, Juyeon Oh, Jin-Ha Yoon, Beom Kyung Kim

Study highlights

Mobile health-technology integrated care in atrial fibrillation patients with heart failure: A report from the mAFA-II randomized clinical trial

5 November 2022
Author(s): Yutao Guo, Giulio Francesco Romiti, Bernadette Corica, Marco Proietti, Niccolò Bonini, Hui Zhang, Gregory YH Lip, mAF-App II trial investigators

Heart Failure (HF) and Atrial Fibrillation (AF) are two of the most common cardiovascular diseases worldwide, both entailing an increased morbidity and mortality [1,2] Sharing common risk factors and... more

Liver fat accumulation more than fibrosis causes early liver dynamic dysfunction in patients with non-alcoholic fatty liver disease

4 November 2022
Author(s): Agostino Di Ciaula, Harshitha Shanmugam, Rogério Ribeiro, Ana Pina, Rita Andrade, Leonilde Bonfrate, João F. Raposo, M. Paula Macedo, Piero Portincasa

Overweight and obesity trends are increasing worldwide, and represent a major health problem [1]. The increase in body fat is also associated with insulin resistance and diabetes [2]. In... more

The long-term prognostic value provided by Coronary CT angiography

31 October 2022
Author(s): Tanya Mohammadi, Babak Mohammadi

Risk stratification of patients has a major role in the prevention and treatment of cardiovascular disease [1,2]. In coronary artery disease (CAD), plaque features have incremental value over total... more

Treatment with COLchicine in hospitalized patients affected by COVID-19: The COLVID-19 trial

30 October 2022
Author(s): Carlo Perricone, Mirko Scarsi, Antonio Brucato, Paola Pisano, Erika Pigatto, Cecilia Becattini, Antonella Cingolani, Francesco Tiso, Roberto Prota, Lina Rachele Tomasoni, Maurizio Cutolo, Marika Tardella, Davide Rozza, Carlo Zerbino, Massimo Andreoni, Venerino Poletti, Elena Bartoloni, Roberto Gerli, COLVID-19 study group, under the auspices of the Italian Society of Rheumatology (SIR), the Italian Society of Infectious and Tropical Diseases (SIMIT) and the Italian Thoracic Society (ITS-AIPO)

The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) related disease (COVID-19) has caused one of the worst pandemics of modern times [1]. As of Sept 1st, 2022, the disease affected over... more

Review Article

Clinical usefulness of testing for severe acute respiratory syndrome coronavirus 2 antibodies

10 November 2022
Author(s): Harry Alexopoulos, Ioannis P Trougakos, Meletios-Athanasios Dimopoulos, Evangelos Terpos

The infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) triggers both B-cell and T-cell responses directed against all viral antigens including the Nucleocapsid (N) and Spike... more

Giant cell arteritis: Update on clinical manifestations, diagnosis, and management

4 November 2022
Author(s): Nicola Farina, Alessandro Tomelleri, Corrado Campochiaro, Lorenzo Dagna

Giant cell arteritis (GCA) – previously known as Horton's disease or temporal arteritis – is the most common vasculitis affecting people older than 50 years [1]. GCA is characterized by granulomatous... more

“How we treat” clinical dilemmas in antiphospholipid syndrome: A case-based approach

19 October 2022
Author(s): Irene Cecchi, Massimo Radin, Silvia Grazietta Foddai, Marta Arbrile, Alice Barinotti, Elena Rubini, Alessandro Morotti, Vittorio Pengo, Dario Roccatello, Savino Sciascia

Antiphospholipid syndrome (APS) is an autoimmune condition characterized by thrombosis (arterial, venous, and microvascular) and/or pregnancy morbidity occurring in subjects persistently positive for... more

WITHDRAWN: Reprint of: Peripheral arterial disease: A growing problem for the internist

16 August 2011
Author(s): Coen D.A. Stehouwer, Denis Clement, Christopher Davidson, Curt Diehm, Jan Willem Elte, Marc Lambert, Daniel Sereni, for the EFIM Vascular Medicine Working Group

This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause.

WITHDRAWN: Reprint of: Proposal for a multidisciplinary approach to the patient with morbid obesity: The St. Franciscus Hospital Morbid Obesity Program

16 August 2011
Author(s): J.W.F. Elte, M. Castro Cabezas, W.W. Vrijland, C.H. Ruseler, M. Groen, G.H.H. Mannaerts

This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause.

WITHDRAWN: Reprint of: Thiazolidinediones for the treatment of type 2 diabetes

16 August 2011
Author(s): J.W.F. Elte, J.F. Blicklé

This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause.

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