The cardiovascular diseases (CVDs) in women could be caused by the expression of traditional cardiovascular risk factors [1–3], and specific female-dependent risk factors as menopause [4]. Hence, hypertension, obesity, and smoking are the strongest CVDs risk factors for ischemic heart disease (IHD) in younger women without a menopausal status (1–4). In this context, recently authors -showed that higher fat accumulation into the mammary gland (lowest breast density) could increase the risk of Major Adverse Cardiac Events (MACEs), independently of body mass index (BMI), and waist-hip ratio circumference (WHR) in pre-menopausal women [4].