The use of anticoagulants has been linked to anticoagulant-related nephropathy (ARN), a condition initially reported in patients treated with warfarin [1]. However, cases have also been documented in patients receiving direct oral anticoagulants (DOACs) [2]. Additionally, vitamin K antagonists (VKAs) have been associated with renal vessel calcification [3]. Despite the anti-inflammatory effect of anti-Xa factors [4], the substantial renal clearance of DOACs, especially of dabigatran, raises concerns regarding their overall impact on renal function.
