Systemic Lupus Erythematosus (SLE) is a multifaceted systemic autoimmune disorder distinguished by a diverse array of clinical manifestations that can potentially impact any organ or system in the body. The disease exhibits a broad spectrum of severity and clinical trajectories, predominantly presenting as persistently active, relapsing-remitting, or frequently flaring phenotypes [1]. Understanding the complexity of SLE is essential, as it not only poses significant challenges for diagnosis and management, but also entails a considerable burden on healthcare systems worldwide.