Elevated uric acid (UA) levels represent an established risk factor for cardiovascular morbidity and mortality [1–3]. Numerous investigations have demonstrated an association between increased UA and the development of cardiovascular diseases (CVDs) such as arterial hypertension [4], coronary artery disease [5], atrial fibrillation [6] or stroke [7]. The pathophysiological interplay between hyperuricemia and CVD is complex, including oxidative stress, endothelial dysfunction, and systemic inflammation [8–10].
