Pulmonary arterial hypertension (PAH) is a progressive disease of the small pulmonary arteries characterized by vascular proliferation and remodelling, increased pulmonary vascular resistances (PVR) and endothelial dysfunction [1]. Over the last years, an increasing attention has been posed on the use of computational fluid dynamic analysis (CFD) in the field of cardiovascular medicine [2], and a growing attention has emerged also in the analysis of PAH. Different studies, using both CFD analysis and 4D-flow magnetic resonance (MRI), have demonstrated that the wall shear stress (WSS), a well-known force in cardiovascular disease, is involved both in the progression and maintenance of PAH [3, 4].
