Heart failure with preserved ejection fraction (HFpEF) is a complex and multifactorial heart disease. It has become the most common type of heart failure (HF), which can be explained in part by its association with obesity and type 2 diabetes (T2D) [1,2]. This association entails greater risk of hospitalization and death, in which the excess of adiposity has been described as a key factor in the physiopathology of the HFpEF, contributing to the left ventricular diastolic dysfunction [3,4].
