Published: 13 May 2025
Author(s): Carlos Hernández Quiles, Ana Casado Díaz, Aurora González Estrada, Marco Antonio Montes Cano, José Salvador García Morillo
Issue: June 2025
Section: Letter to the Editor

Familial Mediterranean Fever (FMF) is the most frequent autoinflammatory disease, characterized by recurrent episodes of fever, abdominal pain, arthritis, and rash. It primarily affects people in the Mediterranean region [1]. FMF is a genetic disorder caused by variants in the MEFV gene (MEditerranean FeVer). Although traditionally considered an autosomal recessive condition, recent findings have demonstrated that it can also be inherited in a dominant manner, with heterozygous carriers presenting clinical symptoms [2].

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