Coeliac disease (CD) is a chronic, lifelong, immune-mediated disorder causing villous atrophy in genetically susceptible individuals upon the ingestion of gluten in the diet [1,2]. It has been recently reported that the global pooled seroprevalence and prevalence of biopsy-confirmed CD are 1.4 % and 0.7 %, respectively, though with some geographical differences, and the incidence has markedly increased over the last three decades [3]. Nonetheless, some studies suggest that a notable proportion of patients remain undiagnosed, [4] due to the lack of symptoms, poor case-finding strategies, or because subtle or mild symptoms can escape medical attention.
