We would like to appreciate Athanasios Manolis and Dimitrios Varvarousis for their interest in our work [1]. In our research, we included consecutive patients with ST-elevation myocardial infarction (STEMI) undergoing percutaneous coronary intervention (PCI) and firstly demonstrated the good predictive value of 4-variable Canada Acute Coronary Syndrome (C-ACS) risk score for evaluating post-acute myocardial infarction (P-AMI) infection [2].