Published: 30 January 2025
Author(s): Stefano Fumagalli, Giuseppe Di Pasquale, Giulio Molon, Giancarlo Agnelli, Niccolò Marchionni, APULEIO Study Investigators
Issue: March 2025
Section: Letter to the Editor

atrial fibrillation (AF) is the arrhythmia most frequently diagnosed in older patients with a prevalence higher than 10 % in subjects ≥70 years [1]. The incidence of venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), also shows an association with age [1]. According to World Health Organization, frailty is a state in which the ability of older people to cope with acute stressors is compromised by an increased vulnerability determined by age-associated declines in physiological reserve and function across multiple organ systems [2].

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