In their large cohort study, Dr. Dicker and his colleagues [1] found that obesity not only does not increase the risk of myocardial infarction (MI) in smokers, but also reduces the excess risk of MI owing to past smoking by 50% and the excess risk owing to current smoking by 22% in individuals aged 40 to 54years. Their finding is not plausible. It appears that both selection bias and confounding played a pivotal role.
