Older adults have been the part of the population most burdened by COVID-19 pandemic. Indeed, the disease mortality rate was reported to rise, in men and women, from 4.6% and 2.5% among those aged 30-39 years to 61% and 48% in individuals older than 80 years, respectively [1]. The age-related trend in mortality and the greater vulnerability of the male gender were confirmed worldwide [2–4].
