Heart failure (HF) is a very prevalent condition associated with high morbidity and mortality rates, thus representing a relevant global health burden. It affects more than 26 million people worldwide [1], with overall prevalence in developed countries of 1-2% in continuous increase, and it is expected to rise up to 3% in U.S. by 2030 [2]. HF is particularly common in the elderly and it is considered one of the main geriatric syndromes, constituting the most frequent cause for hospitalization among older adults [3].
