We have read the article of Kherad et al. with great interest. The authors elaborate on the “less is more” principle, which has become quite relevant in various areas of medicine including cancer [1]. In the last few years, we have observed milestones in research, personalized medicine and digital health. Following these advances, ample access to information has increased awareness outside the labs and the wards. However, each coin has two sides and so does awareness leading to overscreening [2].