With the emergence of coronavirus disease 2019 (COVID-19) pandemic, there has been an exponential rise in the number of scientific publications to convey relevant information about this novel disease [1]. Some data suggest that original investigations related to COVID-19 are published in a fairly shorter time frame by some journals compared with non-COVID articles, which might affect the quality and rigor of these original investigations [2]. Despite these concerns, there is a lack of an objective analysis to study the rigor of original clinical investigations related to COVID-19.