Published: 11 May 2025
Author(s): Cesare Cuspidi, Rita Facchetti, Fosca Quarti-Trevano, Raffaella Dell’Oro, Andrea Faggiano, Giuseppe Mancia, Guido Grassi
Issue: May 2025
Section: Original Article

Left atrial (LA) anatomical remodeling, detected by measuring the diameter or, more comprehensively, the volume with echocardiography is regarded as a marker of left ventricular (LV) diastolic dysfunction reflecting an altered dynamics of LV relaxation and filling [1,2]. Therefore, LA enlargement (LAE) is thought as a compensatory mechanism aimed at counterbalancing the increase in LV chamber stiffness due to both structural and functional alterations [3]. It should be noted, however, that LAE may occur before development of frank LV structural and functional alterations such as LV hypertrophy (LVH), systolic or diastolic LV dysfunction [4,5].

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