With great interest, we read about the study by Tonelli et al. on the predictive value of nasal pressure swing (Pnose) in assessing respiratory support dependency among patients with acute hypoxemic respiratory failure (AHRF) treated with high-flow nasal oxygen (HFNO) [1]. Their findings provide a valuable contribution to understanding respiratory effort as a determinant of HFNO success or failure. However, several aspects warrant further discussion and refinement to enhance the applicability and clinical impact of the study's conclusions.
