Published: 8 June 2020
Author(s): Lu-Xi Zou, Ling Sun, Susanne B. Nicholas, Yan Lu, Satyesh Sinha K, Ruixue Hua
Section: Original article

Glomerular filtrate rate (GFR) is the most useful index of kidney function. Reduction of GFR may indicate chronic kidney disease (CKD) or acute kidney injury (AKI) [1]. CKD is a growing global health concern, and a risk factor for end-stage renal disease (ESRD), cardiovascular disease (CVD), and mortality [2,3]. GFR is central to CKD diagnosis and management and is important in appropriate medication dosing. Therefore, having a precise and convenient measure of GFR would assist in preventing or delaying the progression of CKD.

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