Chronic kidney disease (CKD) affects 8-16% of the population worldwide and is a huge global health issue, given its strong association with higher cardiovascular morbidity and mortality, progression towards end-stage renal disease, and other complications including cognitive decline, mineral bone disease and anaemia [1]. Despite huge efforts to identify novel and more specific kidney biomarkers [2], estimation of glomerular filtration rate (GFR) remains the mainstay of initial CKD diagnosis, its staging, and its subsequent management.
