October 2015

20 Articles

No Section

Social deprivation and hospital admission rates, length of stay and readmissions in emergency medical admissions

14 October 2015
Author(s): Seán Cournane, Declan Byrne, Richard Conway, Deirdre O’Riordan, Seamus Coveney, Bernard Silke

Patients from deprived backgrounds have a higher in-patient mortality following an emergency medical admission. How deprivation relates to the admission or readmission incidence rates, episode length... more

Letter to the Editor

Cryofibrinogenemia and risk of cancer in cryoglobulinemic patients without vasculitis criteria

27 October 2015
Author(s): Martin Michaud, Guillaume Moulis, Bénédicte Puissant, Pierre Cougoul, Laurent Sailler

Cryofibrinogen is a cryoprotein that forms only in plasma and not in serum. In patients screened for a cryopathy, prevalence of cryofibrinogenemia varies from 12% to 51% [1–3]. Most studies... more

The pursuit of excellence in a climate of cost containment

2 October 2015
Author(s): Fabio Ghezzi, Antonella Cromi, Maurizio Serati, Stefano Uccella

We have read with great interest the article by Pavan and Macchi [1] that brings into focus the implications of the changed economic environment for healthcare managers running organizations with a... more

Letters to the Editor

Safe site selection for chest drain insertion by trainee physicians — Implications for medical training and clinical practice

27 October 2015
Author(s): John P. Corcoran, Robert J. Hallifax, Ambika Talwar, Ioannis Psallidas, Najib M. Rahman

The number of patients with symptomatic pleural disease who require diagnostic and/or therapeutic intervention is increasing. Many of these patients will present acutely to emergency departments or... more

Mechanical thrombectomy as an alternative to thrombolysis in embolic stroke

2 October 2015
Author(s): Oscar M.P. Jolobe

Although both atrial fibrillation and cerebral embolism are risk factors for haemorrhagic transformation of cerebral infarction [1], it is the fact that thrombolysis compounds this risk [1] which... more

Original Article

The association between admission systolic blood pressure of heart failure patients with preserved systolic function and mortality outcomes

30 October 2015
Author(s): Yossi Rosman, Eran Kopel, Gadi Shlomai, Ilan Goldenberg, Ehud Grossman

Heart failure is a major cause of death and disability and poses a significant public health concern. Approximately half of the patients admitted with heart failure, have preserved left ventricular... more

Diastolic dysfunction diagnosed by tissue Doppler imaging in cirrhotic patients: Prevalence and its possible relationship with clinical outcome

29 October 2015
Author(s): Calogero Falletta, Daniela Filì, Cinzia Nugara, Gabriele Di Gesaro, Chiara Minà, Cesar Mario Hernandez Baravoglia, Giuseppe Romano, Cesare Scardulla, Fabio Tuzzolino, Giovanni Vizzini, Francesco Clemenza

Cirrhotic cardiomyopathy has been characterized by impaired contractile response to stress and/or altered diastolic relaxation, with electrophysiological abnormalities in the absence of known cardiac... more

The association between glycated hemoglobin levels and mortality in non-diabetic elderly subjects

28 October 2015
Author(s): Alon Grossman, Yichayahou Beloosesky, Agatha Schlesinger, Anat Gafter-Gvili, Nira Koren-Morag, Joseph Meyerovitch, Avraham Weiss

Glycated hemoglobin (HgbA1c) is extensively used as a screening tool for the diagnosis of diabetes mellitus (DM). Although its prognostic value among diabetics has been extensively studied, similar... more

Troponin levels within the normal range and probability of inducible myocardial ischemia and coronary events in patients with acute chest pain

27 October 2015
Author(s): Alberto Bouzas-Mosquera, Jesús Peteiro, Francisco J. Broullón, Ignacio P. Constanso, Jorge L. Rodríguez-Garrido, Dolores Martínez, Juan C. Yáñez, Hildegart Bescos, Nemesio Álvarez-García, José Manuel Vázquez-Rodríguez

Patients with suspected acute coronary syndromes and negative cardiac troponin (cTn) levels are deemed at low risk. Our aim was to assess the effect of cTn levels on the frequency of inducible... more

Risk and mortality of gastrointestinal hemorrhage in patients with thrombocytopenia: Two nationwide retrospective cohort studies

23 October 2015
Author(s): Po-Han Lo, Yu-Feng Huang, Chuen-Chau Chang, Chun-Chieh Yeh, Chia-Yau Chang, Yih-Giun Cherng, Ta-Liang Chen, Chien-Chang Liao

The association between thrombocytopenia (TP) and gastrointestinal hemorrhage was not completely understood. The purpose of this study is to evaluate the risk of gastrointestinal hemorrhage and post-... more

Characteristics and temporal pattern of the readmissions of patients with multiple hospital admissions in the medical departments of a general hospital

23 October 2015
Author(s): María Matesanz-Fernández, Rafael Monte-Secades, Iria Íñiguez-Vázquez, Davis Rubal-Bran, Héctor Guerrero-Sande, Emilio Casariego-Vales

Patients with multiple hospital admissions represent a small percentage of total hospitalizations but result in a considerable proportion of the healthcare expenditure. There are no studies that have... more

Pulmonary embolism, acute coronary syndrome and ischemic stroke in the Spanish National Discharge Database

22 October 2015
Author(s): Ricardo Guijarro, Javier de Miguel-Diez, David Jimenez, Javier Trujillo-Santos, Remedios Otero, Raquel Barba, Manuel Monreal

Venous and arterial thrombosis share a number of pathogenic mechanisms, but the burden of pulmonary embolism (PE) has not been consistently compared with that in other arterial diseases.

Is diabetes mellitus a risk factor for venous thromboembolism? A systematic review and meta-analysis of case–control and cohort studies

21 October 2015
Author(s): Karim Gariani, Thomas Mavrakanas, Christophe Combescure, Arnaud Perrier, Christophe Marti

Diabetes mellitus is a well-established risk factor for atherosclerotic disease, but its role in the occurrence of venous thromboembolism (VTE) has not been elucidated. We conducted a meta-analysis... more

Primary PCI is associated with different cardiac autonomic patterns in relation to the site of myocardial infarction

21 October 2015
Author(s): Eleonora Tobaldini, Elisa M. Fiorelli, Marta Prado, Maddalena A. Wu, Andreia Queiroz, Tomas Kara, Giorgio Costantino, Armando Belloni, Lorenzo Campi, Paolo Danna, Roberto Sala, Maurizio Viecca, Nicola Montano

Reflex alterations of cardiac autonomic modulation have been described after acute myocardial infarction (AMI). The non-homogeneous autonomic innervation of the heart gives reason of different... more

Atrial fibrillation, CHA2DS2-VASc score, antithrombotics and risk of non-traffic-, non-cancer-related bone fractures: A population-based cohort study

19 October 2015
Author(s): Hui-Chin Lai, Wu-Chien Chien, Chi-Hsiang Chung, Wen-Lieng Lee, Tsu-Juey Wu, Kuo-Yang Wang, Chia-Ning Liu, Tsun-Jui Liu

Accidental bone fractures are a major cause of premature disabilities and death. Whether atrial fibrillation (AF) treated with or without antithrombotics correlates with occurrence of such events... more

Acute and chronic diseases as part of multimorbidity in acutely hospitalized older patients

14 October 2015
Author(s): Bianca M. Buurman, Wijnanda J. Frenkel, Ameen Abu-Hanna, Juliette L. Parlevliet, Sophia E. de Rooij

To describe the prevalence of multimorbidity and to study the association between acute and chronic diseases in acutely hospitalized older patients

Physicians and alternative medicines in “The Barber of Seville” by Gioachino Rossini: A bicentennial debate

13 October 2015
Author(s): Michele Augusto Riva, Iacopo Bellani, Massimo Turato, Giancarlo Cesana

The year 2016 marks the bicentennial anniversary of the premiere of “The Barber of Seville” by Gioachino Rossini (1792–1868). This opera buffa, one of the most renowned in the world, puts on stage a... more

Review Article

Prevention of colorectal cancer: How many tools do we have in our basket?

20 October 2015
Author(s): Luca Roncucci, Francesco Mariani

Prevention is the main strategy in order to reduce colorectal cancer incidence and mortality. It can be accomplished through primary prevention, using measures affecting factors known to confer... more

Patent foramen ovale: Unanswered questions

18 October 2015
Author(s): Mohammad Khalid Mojadidi, Panagiota Christia, Jason Salamon, Jared Liebelt, Tarique Zaman, Rubine Gevorgyan, Nariman Nezami, Sanaullah Mojaddedi, Islam Y. Elgendy, Jonathan M. Tobis, Robert Faillace

The foramen ovale is a remnant of the fetal circulation that remains patent in 20–25% of the adult population. Although long overlooked as a potential pathway that could produce pathologic conditions... more

IgG4-related disease: A relatively new concept for clinicians

16 October 2015
Author(s): Lilian Vasaitis

IgG4-related disease (IgG4-RD) is a recently recognized chronic fibrotic inflammation, which can affect almost every organ, and may come to clinical attention first due to visible organ swelling or... more


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