Published: 8 September 2025
Author(s): Guangdong Wang, Tingting Liu, Wenwen Ji, Zhihong Shi
Issue: October 2025
Section: Letter to the Editor

We appreciate the authors’ important contribution on post-discharge outcomes in community-acquired pneumonia (CAP)[1]. One key concern lies in the treatment of “immunosuppression” as a unitary exposure in the main analysis, despite the methodological distinction between disease-related and drug-related causes. While this approach improves model parsimony, it underestimates clinically meaningful heterogeneity.

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