Published: 15 June 2023
Author(s): Aurore Abel, Estibaliz Lazaro, Mamy Ralazamahaleo, Emma Pierrisnard, Benoit Suzon, Fabrice Bonnet, Patrick Mercié, Julie Macey, Moustapha Agossou, Jean-Francois Viallard, Christophe Deligny, Etienne Rivière
Section: Original article

Antisynthetase syndrome (ASyS), a rare and heterogeneous systemic autoimmune disease, is classified as a subtype of idiopathic inflammatory myopathy (IIM). It is associated with at least one of the following six criteria: interstitial lung disease (ILD), myositis, non-erosive arthritis, Raynaud's phenomenon, mechanic's hands, and unexplained fever. These manifestations are associated with autoantibodies against aminoacyl-transfer RNA synthetase (anti-ARS).


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