Vascular diseases are the main cause of death in developed countries [1]. Despite much progress has been made to improve the management of these diseases, it is difficult to predict those patients at high risk of mortality. Biomarkers are a relatively new clinical toolset used in the current precision medicine approach. This is a medical model that proposes the customization of healthcare, with medical decisions, treatments or practices being tailored to a subgroup of patients, instead of a “one-drug-fits-all” model.