Anaphylaxis is an acute, usually rapidly developing, systemic (involving multiple organs) allergic reaction and, among the various clinical forms of allergy, it is the most severe and potentially life-threatening [1]. In the last decades, an epidemiologic increase of anaphylaxis, mainly in terms of hospitalization, has been observed [2]. This is particularly the case of food allergy [3] [4]. The overall incidence of anaphylaxis varies between 50 and 112 episodes per 100.000 person-years while its prevalence is 0.3–5.1% according to various epidemiological and classification factors [5].