Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with female predominance: cardiovascular disease (CVD) is the leading cause of morbidity and mortality. Accelerated atherosclerosis and coronary artery disease (CAD) are major contributors to the pathogenesis of CVD in SLE patients [1,2]. Previously, it was thought that CAD was a condition affecting exclusively older men; however, patients with SLE (young female-predominant) have an increased risk of CVD compared with the general population [2].